Director, Medical Science Liaison
Department: 122 Medical AffairsLocation: Waltham, MA
Company Overview:
Dyne Therapeutics is discovering and advancing innovative life-transforming therapeutics for people living with genetically driven neuromuscular diseases. Leveraging the modularity of its FORCE™ platform, Dyne is developing targeted therapeutics that deliver to muscle and the central nervous system (CNS). Dyne has a broad pipeline for neuromuscular diseases, including clinical programs for myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD) and preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. For more information, please visit https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook.
Role Summary:
The Director, Medical Science Liaison (MSL) is an experienced field medical expert who plays a strategic role on the field medical team with depth and breadth of business acumen, therapeutic knowledge and serves as an informal leader on the team. The person in this role will be a customer facing, field-based extension of our Medical Affairs team. The MSL’s key objective is to create impact through advancing clinical practice within the assigned territory that leads to improved patient outcomes. This individual will serve as a key scientific resource, engaging with healthcare professionals (HCPs), key opinion leaders (KOLs), and other stakeholders to provide scientific and clinical support for our portfolio.
Primary Responsibilities Include:
- Builds awareness of the company within the medical community and develops strategic KOL/territory engagement plans aligned with the medical strategy
- Supports clinical research (investigator-initiated and company-sponsored), speaker development, and training as needed
- Demonstrates thorough knowledge of the company, its investigational products, and current medical research
- Maximizes attendance at national and regional conferences to gather insights, assess the competitive landscape, and strengthen relationships
- Leads identification and mapping of key KOLs within the therapeutic area, driving engagement strategies
- Provides strategic leadership within the MSL team as a peer leader, motivator, and problem solver
- Manages top-tier KOL relationships, synthesizes high-level medical insights, and informs company medical strategies
- Collaborates cross-functionally (clinical, regulatory, market access) to advance business and scientific goals
- Mentors junior MSLs and contributes to team strategy development
- Acts as a subject matter expert for internal stakeholders, including marketing, sales, and clinical teams
- Establishes and develops HCP relationships, engaging in activities such as data discussions, clinical trials, and addressing patient journey barriers
- Responds to unsolicited information requests in a timely, accurate, and compliant manner
- Collaborates with internal teams (HEOR, access, marketing, sales) to maintain a customer-centric, compliant approach within assigned territory
- Ensures compliant dissemination of scientific and clinical information to healthcare providers
- Manages administrative tasks (e.g., Veeva CRM, expense reports, compliance modules) efficiently, including customer profiling and keeping CRM information up to date
Education and Skills Requirements:
- Advanced scientific degree or equivalent required (e.g., MD, PhD, NP, PharmD, PA)
- 10+ years of MSL experience
- Clinical experience within neuromuscular disorders (e.g., DMD, DM1) preferred; rare disease experience considered
- Strong knowledge of investigational products and the neuromuscular space, including emerging data
- In-depth understanding of clinical trial and investigator-sponsored study processes
- Proven ability to work effectively within multidisciplinary teams
- Clear understanding of MSL role and responsibilities
- Skilled in building and maintaining relationships with KOLs through scientific expertise and follow-through
- Able to communicate research results clearly to diverse audiences
- Strong communication skills (written, verbal, presentation) for building relationships with colleagues
- Expert in planning, prioritizing, and executing tasks efficiently
- Capable of working independently and managing time in a home office
- Adaptable in ambiguous and dynamic environments
- Leverages past neuromuscular relationships to support study enrollment and site communication
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The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.
This description is not intended to be constructed as an exhaustive list of duties, responsibilities, or requirements for the position. This position may change or assume additional duties at any time. The employee may be requested to perform different or additional duties as assigned. All Employees are expected to adhere to all company policies and act as a role model for company values.
Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
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